Research
Overview
Our lab studies basal ganglia and reward circuitry in motivation or repetitive behavior. Much of our work has been focused on the projection neurons in the striatum but we also examine stratal input and output regions. We employ an array of techniques including cell subtype multi-comic sequencing, chromatin immunoprecipitation, protein expression, cell and organelle morphology analysis, optogenetics, chemogenetics, calcium imaging, viral-mediated gene transfer, CRISPR genome and epigenome editing tools, behavioral paradigms to study these circuits in to better understand the impact of drugs of abuse, stress, or stereotypy behavior on brain molecular and circuit mechanisms.
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Lab Projects
Lab Funding
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Current Funding
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Previous Funding
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